First Believers in Frontier Founders.
We back technical teams at the nucleus of their journey, rewiring the fabric of modern life through biology, food, and industrial systems.
Where frontier founders begin
Sector focus
Programmable Biology
Where computation meets biology. Tools that accelerate discovery and systems that produce at scale.
Food Technology
Rewiring the world’s largest supply chain - from how we grow to what we eat. Transforming agriculture, food production, and distribution to build a more resilient food system at scale.
Neo Industrials
Backing the next generation of industrial infrastructure - energy, manufacturing, materials, and supply chains redesigned for a resource-constrained world.
Investment approach
First checks
Most investors show up once there is momentum. We engage when direction is still being encoded. With checks of up to €1,0M we lead or co-lead as your first believers.
Thesis-driven
We are thesis-driven high conviction investors with a concentrated portfolio active in Europe and the US.
Purpose-built
You can’t apply the SaaS playbook to deep-tech. Our support model is built for scientific ventures, tailored to the pace, complexity, and capital needs of frontier innovation.
Philosophy
Beyond investment
We bring the techno-economic depth, industrial networks, and operational experience necessary to accelerate frontier tech adoption and turn ideas into scalable, category defining companies.
Partnership
We speak the language of technical teams. We invest selectively and stay close. The partnership is direct, open, pragmatic, and personal. Founders only work with decision-makers.
Impact
We back a new breed of companies where resilience is inherently engineered with viable unit economics and lower footprint.
Numbers that matter
Commitments
Spotlight
.svg)
.jpeg)
.jpeg)
.svg)
All commitments
.svg)
.svg)
%20(1).svg)
Founder perspectives
Testimonials
“Nucleus, with their exceptional network, was the most influential and valuable partner in the first years after we incorporated.”
Dr. Sara & Max Marquart
.jpeg)
“We see a VC partnership as an early hire, and Nucleus would unquestionably be our first. They provide the guidance, structure, and execution clarity that meaningfully shifts outcomes."
Juan Garzon & Ruben Lopez
“The team is very responsive, transparent and honest from the start. They clearly demonstrate a strong understanding of scientific and technical areas - which makes them a fantastic partner.”
Charlie Silver
“Nucleus is the deep‑tech investor that quietly does the real work - fiercely supportive, founder‑first, and willing to lean in on the toughest, highest‑impact problems.”
Dr. Mathias Bösl
Hands on. True partners.
At the Nucleus of Frontier Founders.
Team
Dr. Isabella Fandrych
Isabella is a General Partner. She focuses on Neo Industrials and corporate relationships. Isabella is an Industrial Engineer by training with a passion for technology and impact.
Maximilian Schwarz
Maximilian is a General Partner. He focuses on Food Tech and Programmable Biology. Max is a hands-on problem solver with a business background and a passion for entrepreneurship.
Dr. Carolina Villa
Carolina is a Principal. She focuses on Programmable Biology. A Bioprocess Engineer by training, Caro is an expert in TEAs and bioprocess scale-up. She also makes kick-ass cocktails.
Supported by a community of world-class industry leaders.
Name
